Development of myocardial tolerance to oxygen deficiency - experimental aspects
نویسندگان
چکیده
منابع مشابه
Development of cardiac sensitivity to oxygen deficiency: comparative and ontogenetic aspects.
Hypoxic states of the cardiovascular system are undoubtedly associated with the most frequent diseases of modern times. They originate as a result of disproportion between the amount of oxygen supplied to the cardiac cell and the amount actually required by the cell. The degree of hypoxic injury depends not only on the intensity and duration of the hypoxic stimulus, but also on the level of car...
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Our present focus on the hypoxic immature heart is driven by clinical urgency: cyanotic congenital cardiac malformations remain the single largest cause of mortality from congenital defects and ischemic heart disease is no more the disease of the fifth and older decades but its origin as well as risk factors are present already during early ontogeny. Moreover, the number of adult patients opera...
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Opiates, chiefly morphine, are commonly known as the best drugs for relief of pain, but due to development of tolerance and the physical or mental dependency the use of these drugs are restricted. Several neuroendocrine complications including diabetes change the antinociception of morphine and the development of tolerance and dependency to this drug. The withdrawal signs in diabetic rats signi...
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ژورنال
عنوان ژورنال: Cor et Vasa
سال: 2009
ISSN: 0010-8650,1803-7712
DOI: 10.33678/cor.2009.171